I’m The Only One With Genius DNA 148
I’m The Only One With Genius DNA chapter 148
Song Jong-ho is Song Ji-hyun’s younger brother.
His father was a member of the SG Group and his mother studied economics until she left the company and became a housewife at home.
The warm and stable childhood of a well-to-do middle-class family has only happy memories.
Song Ji-hyun was also famous for her pretty face, but her younger brother added.
Song Jong-ho was an idol of local mothers.
“Oh, Jong Ho is prettier than any other girl.”
“When she grows up, she’ll make a lot of girls cry.”
Everyone who saw it complimented and loved it, saying that he was pretty and handsome.
In fact, as he grew up, Song Jong-ho became an all-around model student who was smart, talkative, and good at sports and studying like my sister.
And it first happened when Song Ji-hyun was a freshman in high school.
“Did you get all that today?”
When Song Jong-ho came back from school and saw him pouring something out of his bag, Song Ji-hyun asked absurdly.
It was full of chocolate.
“Uh.”
“May I read the letter?”
“No letters.”
“Then can I eat chocolate?”
“Yes, sister. Eat it all.”
“I think you have your own hand-crafted……. Can I give you everything without eating?”
“I don’t like sweets anyway. And you’re a sweet ghost. We’ll name him whipped cream. What’s whipped cream to a retriever?”
“When he grows up and gives birth to a baby, he’ll name it Brownie.”
Song Ji-hyun said as she picked up a chocolate.
“Really, I’m eating?”
“I told you to eat it all.”
“What should I do if she follows my sister around like this?”
Song Ji-hyun said as she peeled the chocolate.
“I only have a real sister.”
“Don’t talk gross nonsense.”
“It’s real…….”
Song Jong-ho said.
“So you shouldn’t hate me.”
“Who hates you when you’re the most popular in school?”
“No, there are a lot of people who hate me. There’s a lot….”
” said the man who just spilled 40 chocolates and letters from his bag.”
“I’m serious. They always curse at me. I can hear you. I’m getting neurosis these days. Now I think I can hear the sound of “Get lost, idiot” even when I turn the pages. I feel like I’m being bullied.”
“Don’t be silly. Don’t I know you? I went to the same school as you a few months ago.”
Song Ji-hyun replied as if she was the same.
“That’s why I’m worried.”
Song Jong-ho said with a gloomy expression.
“My sister went to high school. There’s no one in school I can trust anymore…….”
Surprisingly, tears formed in Song Jong-ho’s eyes.
Song Ji-hyun was surprised to see her teary eyes wiped away.
“Are you crying?”
“No.”
Song Jong-ho went straight into his room as if he were running away.
“What…….”
Shocked by Song Jong-ho’s tears, Song Ji-hyun contacted his junior in middle school.
He was a junior who became close while working in a literary club.
He was a junior who became close while working in a literary club.
“Na Eun, are you in the same class with Jong Ho?”
Yes, it’s been a while. Do you like high school?
“Yes. Do you know how Jong Ho is doing these days?”
Jong Ho? Jong Ho is doing great. Now that she’s gone, there’s only Jong Ho in Seongseo Middle School.
“Yes……. Are you outcast or anything?”
What? Outcast? No way.
“…….”
Jong Ho is more popular with boys. They’re good at soccer, and when they’re together, girls pay attention to them. For girls…Ask them how many chocolates they got today. I heard they don’t fit in the bag and take it home for a few days.
“….Yes, thank you.”
Song Ji-hyun came out of his room and passed by Song Jong-ho’s room.
A little less than three months old, the golden retriever whipped cream approached and licked Song Ji-hyun’s toes.
Song Ji-hyun embraced the puppy and soothed the strange anxiety.
Five months later.
Song Jong-ho fought with his classmates.
I heard that a child who had never argued or raised his voice with anyone in his life even punched for the first time.
Jong Ho is a little weird these days…….
Na-eun, who answered Song Ji-hyun’s phone call, said.
He’s a little sensitive to coughing and sniffling. But these days, I get irritated. We fought like that again.
“Really?”
He said his head was open and everyone around him seemed to see his thoughts flowing out. That’s too much of a concern…
***
“I got a doctor and he said he was schizophrenic.”
Song Ji-hyun said.
“Are you being treated steadily since then?”
asked Ryu Young-joon.
“Yes, I once thought I was almost cured, but it happened again. Since then, I’ve been on medication at the hospital.”
“……. It must be very difficult.”
“Cho Hyun-byung is a disease that is so hard that it is called cancer of the mind cancer. They say there are endless hallucinations, hallucinations, delusions, and unconsciousness.”
Song Ji-hyun said.
“My brother is still good at catching the disease early on, but he’s still dangerous.….’
“…….”
“Recently, my father took him to the hospital and hurt himself while he was away for a while. I tried to jump out of the window.”
“Really?”
It stung a little.
“Yes, but a man there caught me, and fortunately, there was no accident.”
“Oh…. That’s a relief.”
“I don’t usually show violence, but I’ve been doing this all of a sudden lately.….I was thinking about it and moved to the next generation hospital. Of course, the next generation of hospitals won’t cure schizophrenia like Alzheimer’s. But the medical staff is good, so I’m here just in case.”
Song Ji-hyun said.
Then the nurse shouted at the doctor’s office.
“Song Jong-ho, come into the doctor’s office.”
“Yes.”
Song Jihyun raised her hand.
As she moved, she turned her head and told Ryu Young-joon.
“I guess you’re done with your treatment. I’ll go and talk to the doctor. See you later.”
***
“Chohyun’s disease is an incurable disease.”
Professor Shin Jung-joo of Song Jong-ho said.
Professor Shin Jung-joo, who worked at Yeonui University Hospital, recently moved to the next generation hospital.
“How is patient Song Jong-ho doing?”
asked Ryu Young-joon.
asked Ryu Young-joon.
“Why would anyone know ask? Dr. Liu, we don’t tell anyone about patient personal information.”
“…. Professor, can you tell me a little bit about schizophrenia?”
“Are you trying to develop a cure for schizophrenia?”
“If possible.”
“It won’t be easy.”
Shin Jung-ju said.
“Dr. Ryu, schizophrenia is a disease that is much more difficult to understand than most cancers. That’s because we don’t know the cause.”
“I don’t know much about it, but I’ve heard it’s not a mental illness, it’s a brain disease. Then I think biology can find its way.”
Ryu Young-joon said.
“Well.”
Professor Shin Jung-joo was briefly lost in thought as he smoothed his chin.
“What do you think is the incidence of schizophrenia, Dr. Ryu?”
“I don’t know. One in a hundred thousand.
“One in a hundred.”
Ryu Young-joon’s eyes widened.
“One in a hundred?”
“Yes, a percentage. And urban patients are more severe, the most typical modern disease.”
Professor Shin Jung-joo said.
“The WHO calls it schizophrenia paradox. Usually, the progress of the disease is better in developed countries. The medical system is well-established. But schizophrenia is the opposite. Compared to the majority of underdeveloped countries in agricultural communities, urban patients have more severe diseases and worse treatment outcomes.”
“……..”
“It’s becoming increasingly urban, and I think it’s going to be a dangerous disease in the future. But the research is too insufficient.”
Professor Shin Jung-joo said.
“Recently, there have been more views that we don’t see as a single disease. Cancer is not a single disease. Just as lung, pancreatic and breast cancer are seriously different, schizophrenia is actually a disease that deserves to be divided into countless diseases, but the medical community doesn’t know it, so it’s becoming schizophrenia.”
“I see.”
“Even if Dr. Ryu develops the drug, it would be unlikely that he can catch all schizophrenia. But if we catch some, many people will have hope and big research will be made. I’ll tell you what I know.”
Professor Shin Jung-joo said.
The symptoms of schizophrenia are generally the concept of “crazy” that people think of.
Even in primitive clan societies, there were people suffering from schizophrenia and hallucinations.
As society developed, they became crazy, sorcerer, or prophet.
I became a ghost or God’s revelation.
In the Middle Ages, a facility called a mental hospital appeared, but in fact, it was not for treatment but for isolation and confinement of schizophrenic patients.
And the devil’s curse was written, and the assault was also inflicted on the patient in the name of evicting it.
They say beating was the cure.
It was a doctor named Philippe Pennell who changed the barbaric paradigm.
– The treatment effect of schizophrenia patients cannot be seen through abuse.
His arguments and movements first organized psychiatry with his followers and succeeded in incorporating ‘mental illness’ into medical concepts.
And after Freud’s psychoanalysis swept the psychiatry community, it was called “Schizophenia.”
“Recently, there was a paper in the journal Nature that found 108 gene locations related to schizophrenia.
Professor Shin Jung-joo found a paper on a computer and printed it.
“I think Dr. Ryu will be interested. Read it.”
***
In the late room, in the office, Ryu Young-joon was reading a paper.
Before turning Rosaline to track down the answer, I wanted to see where medicine now went to conquer the disease.
Rosalyn, can you check the facts?”
asked Ryu Young-joon.
Yes, go ahead.
“Chohyun’s disease has a strong genetic power. Between twins, there is a 50% chance that one person will have schizophrenia. If both parents are schizophrenic, there is a 10% chance that their children will get schizophrenia.”
– That’s right.
Rosaline replied.
Genes don’t decide on their own. It’s not like, “If genetic information is like this, you’ll get schizophrenia,” but “If genetic information is like this, you’re very likely to get schizophrenia.”
Genes don’t decide on their own. It’s not like, “If genetic information is like this, you’ll get schizophrenia,” but “If genetic information is like this, you’re very likely to get schizophrenia.”
“Most of the time, the brain produces too much dopamine to be controlled.”
-Dopamine is not the only problem, it is the result of interaction of three neurotransmitters, including serotonin and glutamate.
“…….”
-And neuropathically, the volume and cross-sectional area of the hippocampus and amygdala nucleus are reduced, resulting in fibroblast failure of the prefrontal temporal lobe region, impairment of nerve fibers, and lack of transparent septum. It affects them, too.
“Is that brain damage causing schizophrenia?”
No, the beginning is more than the expression of neurotransmitters. It hits the brain, it gets worse in the brain, and the amount of neurotransmitter releases gets worse. Malicious feedback.
“Can Casnine target the brain as if it were treating genes?”
Are you going to send Cassnine to the brain with your brain?
“The way to bypass dendritic cells is to send casnine to immune cells, but not brain cells.”
But if you use the virus, you’ll use the Adeno Associate Virus, which can’t touch 100 genes at a time.
“What if you put in the normal genes yourself?”
The same thing is, you can’t put 100 genes into a virus.
“…….”
Ryu Young-joon tapped the [listen to advice] button.
“I don’t care if it’s a crazy idea, so give me anything.”
Put the gene in the mitochondria.
“Mitochondria?”
– An energy-producing organ that exists within the cell. And it’s a kind of bacteria.
“That’s right.”
Mitochondria are part of the tissue in the cell.
It is an organization that produces power like a generator in a factory.
In the mysterious microworld, the standard of single life is obscured, and so is the identity of mitochondria.
Bacteria that penetrated into eukaryotic cells billions of years ago and became symbiotic.
It is a primitive creature that has become part of eukaryotic cells in that state.
It is now unclear whether it is a separate or inanimate creature that can be distinguished from human somatic cells.
– Mitochondria have their genes. The size is quite large, so you can carry about a hundred additional genes. Cultivate mitochondria back from the patient’s cells. We’re going back to primitive bacteria. And we’re putting about 100 genes into it.
Rosaline said.
– Inject it into the nasal cavity and send it to the brain to get into the brain cell.
“I asked for some crazy ideas, but this…….”
– Mitochondria are part of human cells, so it’s safe to enter the brain cells. But now that the genes are manipulated, the new biomaterials produced there are different from the conventional ones.
Rosaline said.
It can cure schizophrenia completely.
“When I was flying in, I gave permission to do probiotics, but it’s much harder.”
Just by putting genetically modified bacteria in the intestines, the KFDA could go on a rampage asking if you’re crazy.
But you’re going to put 100 genetically modified bacteria in your brain to get into your brain cells?
But you’re going to put 100 genetically modified bacteria in your brain to get into your brain cells?
“Phew…….”
Ryu Young-joon sighed deeply.
I’m The Only One With Genius DNA chapter 148
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