I’m The Only One With Genius DNA 51
I’m The Only One With Genius DNA chapter 51
Avio (6)
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Neuropsychiatry at Yonsei University Hospital.
In the hospital room, there were a dozen elderly people lying on their beds.
It is the new institution responsible for a powerful clinical trial of stem cell-based Alzheimer’s.
News all over the world was buzzing when there was talk of clinical trials, but a month later, it became quiet.
In the meantime, no patients showed any signs of improvement.
Professor Shin Jung-joo of clinical trial came in.
“How are you?”
He asked Park Ju-nam’s patient.
“······.”
Park Ju-nam did not reply.
Ryu Young-joon came behind Shin Jeong-ju, who was looking at medical treatment by asking a few more questions.
Yeon’s hospital was selected by Professor Ko In-guk. Now, instead of receiving written reports like before, Ryu Young-joon visited him once a week to check the progress.
I was a little sorry to the doctor in charge, but I couldn’t feel better if I didn’t do this.
Fortunately, Professor Shin Jung-joo did not feel uncomfortable about Ryu Young-joon’s visit.
Shin Jeong-ju was acquainted with Professor Ko In-guk because he heard everything about what happened to him.
“We’ll have to wait and see.”
Shin Jung-ju told Ryu Young-joon.
“Yes, sir. It will take some time for the newly-differentiated brain nerve to settle down. A month may not be enough.”
Ryu Young-joon replied.
During Shin’s treatment, Ryu Young-joon also examined patients in synchronization mode. In fact, this episode was more accurate than the doctor’s.
Most of the patients are on the verge of treatment, even though they are not visible.
Biological sanctions of the original cell therapy type are often like this when tested.
As if it were an incubation period, the change was not visible on the outside, but it was a time of consideration in which behind-the-scenes work was carried out inside.
Beyond a certain point, the effectiveness of the drug will soar on the index scale from that moment.
“Oh, hello, teacher!”
Someone popped out of the back and greeted Ryu Young-joon.
It was Kang Hyuk-soo.
I’ve seen Ryu’s face quite often, but this is the reaction whenever Ryu Young-joon appears.
In fact, Kang Hyuk-soo didn’t show his face, but guessed that the money in the mailbox belonged to Ryu Young-joon.
Whenever I saw him, I was grateful and glad to see him, but Ryu Young-joon was a little burdened.
I’m here just in time for you not to be here.
Ryu Young-joon already felt tired, but he greeted me happily.
“Hello.”
“Do you want this, sir?”
Kang Hyuk-soo held out a chocolate bar.
“It’s okay, but isn’t it time to open a taxi?”
“I come five or six times a day to see my grandmother.”
Kang Hyuk-soo smiled nicely.
“I’m absolutely pathetic, old man.”
A grandmother by the window said teasingly.
She was an early Alzheimer’s patient, most sober here.
“I wish my husband could do that, too.
Kang Hyuk-soo scratched his head with an awkward expression and held out a chocolate bar to Ryu Young-joon again.
“Teacher, this is all I can give you. Eat this and cheer up!”
“Thank you, but it’s okay. Give it to the doctor.”
Ryu Young-joon gave up chocolate to Shin Jung-ju.
“I don’t even have your car yet, but I’m a little ashamed to get this.”
Shin Jung-ju said with a smile.
“Hehe. He’ll be fine soon.”
Kang Hyuk-soo said, blinking his wrinkled eyes.
“Isn’t that right, Grandma?”
He turned his head toward Park Ju-nam and asked.
Park Ju-nam lifted his head gently.
Flinch.
Ryu Young-joon’s shoulders were wriggling. This is because a message window came to mind as Park Ju-nam and his eyes met.
Synaptogenic.
It’s a word that means a new synapse is formed.
This means that there is a connection between the neurons that have grown up.
If so, there will be a reaction.
“Shaving.”
Park Ju-nam said facing Kang Hyuk-soo.
There was a moment of silence. Kang Hyuk-soo was frozen and stuck.
Park Ju-nam stared at him and said in a subdued voice.
“Shave.”
“Now······ What ····.”
Shin Jung-ju stepped up in front of Kang Hyuk-soo, whose eyes got bigger due to shock.
“Grandmother, grandfather, do you recognize him?”
“······.”
Park Ju-nam nodded slowly.
It’s a very feeble level, but her cognitive ability and memory came back.
It was proof that the battle for Alzheimer’s disease and stem cell therapy, which took place in patients’ brains over the past month, had been put to an end.
***
Over time, fully grown brain neurons began to settle one by one in all patients.
Once in recovery, progress was made at a tremendous rate.
Only four days after Park Ju-nam brought up shaving, patients who incontinence disappeared.
By the time it was a week, patients who had difficulty moving could move slowly on their own.
In the second week, patients’ cognitive and thinking abilities recovered to a similar level as before they suffered from Alzheimer’s.
“I’ll count backwards, subtracting from 100 to 7 in my head. Grandmother.”
Park Ju-nam replied to the question of Shin Jeong-
“100. 93, ·······86? And, uh····. 79?”
“That’s right. Can you do more?”
“72! And, let’s see, let’s see. If there’s 3 left, it’s 5 plus 2, 65?
Shin Jeong-ju’s arm gave me goosebumps.
He couldn’t even subtract one from 100 before treatment.
Now, thinking ability may be above the average value of older people.
No signs of side effects such as stem cells developing tumors in the brain have been detected.
MRI data showed that the cerebral cortex, which had been atrophied, had clearly expanded and the hippocampus, which had been atrophied, had normalized. The enlarged ventricle became as small as a normal brain.
We still have to wait and see, but we can conclude carefully as a doctor.
“It’s not a stage where you can use the expression “completely cured. But it’s a significant improvement.”
Shin Jung-ju said.
After receiving his inquiry, Science’s editor Jesse felt his heart beating so loudly that he was about to be smashed.
“Thank you··········.”
Jessie’s voice trembled.
This is different from glaucoma treatment in terms of impact.
Phase 1 clinical success of stem cell therapy aimed at treating Alzheimer’s.
Aside from academics and hospitals being turned upside down, what kind of repercussions will it have on society as a whole?
Previously, there were quite a few drugs developed to treat Alzheimer’s.
Some of them used stem cells for complete recovery.
Many such studies were conducted at Allbio, Nature Genic, and Tritney Clinic in Fukuoka. There are many things that even have clinical ones. Even if you search Google for “Stem Cell Alzheimer’s” now, you’ll find a lot of them.
The problem is that all of them have failed.
New drugs and pharmaceutical companies, which entered the field with overflowing spirit of ambition and challenge, were overflowing, but all of them collapsed. It was too difficult.
After all, only four products have been approved by the U.S. FDA, including Namenda, Arisect, Axelon, and Lazarin.
And the four are only enough to alleviate Alzheimer’s symptoms but slow down.
There was no drug in the world that had potential to regenerate and cure brain cells that had already been damaged. So far, it has been.
The number of patients with Alzheimer’s disease is about 80 million throughout the world.
Some predict that the number will soar steeply every year, reaching 270 million by 2050.
‘If this technology is commercialized, that kind of future won’t come.’
Given the nature of the disease, not only saving a person’s life and quality of life, but also the financial and emotional costs of society that they incur?
Indeed, it is not enough to win the Nobel Prize ten times.
“Are you going to interview Dr. Ryu?”
Shin Jung-ju asked.
“Yes, of course.”
“But Dr. Liu is so busy these days that he may not be able to interview you.”
“Really?”
“I’ve heard this before, but he’s expanding his business these days, writing an Alzheimer’s thesis, and preparing for a new drug clinical trial. They can’t sleep for more than four hours a day.”
“Ou·····.”
“Wouldn’t you be writing a paper soon instead? I’m sure it’ll be in Science.”
“Regardless of what papers come out this month, it’s a cover without asking or questioning.”
“I’m looking forward to it, too. Thanks to Dr. Liu, I’m putting my name on Science.”
Shin Jung-joo smiled.
***
“Bamboo············.”
All 122 new drug patents for 34 diseases have been registered.
Lawyer Lee Hye-won was lying on the desk of the office.
Even if multiple new drugs are used in a single disease, 34 patents are used.
If I had two more, I would’ve overworked myself.’
But the experimental data of 122 new drugs were all good. If you look at the data sent from Cell Bio, every single one of them was successful.
Does this make sense?
Usually, the process of developing a new drug involves beating thousands of candidate drugs into disease model cell stocks and then picking out one that has medicinal effects.
They are discovered with thousands and tens of thousands of possibilities.
But didn’t Dr. Liu test hundreds of thousands of candidate materials alone?
How the hell did you know these substances worked?
If you compare it roughly, it’s all right that someone talked about it in a brain-based way.
As if it’s a drug that’s already out there, we’ll pull out 122 candidates, then we’ll just do the appropriate experiments, make the data, and register all the patents?
It’s amazing how the conveyor belt looks like it’s rolling.
There have been all kinds of stories about Ryu Young-joon in the news, but this was more mysterious to Lee Hye-won than reverse differentiated stem cells and glaucoma.
It’s not just a genius.
Isn’t there an alien in the basement of the house?
I had a silly imagination.
Clank.
At the sound of the door opening, I took my butt half off the chair and found it was Park Joo-hyuk.
“Hello.”
“I thought you were a guest.”
Lee Hye-won smiled and sat down as if she had leaked steam. Then, he stopped in an awkward position.
“Uh ·····?”
This is because a ray of anxiety suddenly passed through my head.
She asked in a trembling voice.
“Oh, brother, do you happen to be…” Dr. Liu didn’t give you another job, did he?”
“Hhhhh. You can’t get away from work, slave. I’ll tie you to that chair now, so don’t think about getting off work.”
Lee Hye-won’s face turned blue.
“Please let me sleep eight hours a day.”
“But you don’t want to miss our CEO even if you’re going through so much trouble, do you?”
“Of course he is. If you miss it, you’re unemployed.”
Lee Hye-won took out the orange juice and poured it out.
“So what’s going on this time?”
“Actually, I’m not here to work. You were tricked, weren’t you?”
“What?”
“I’m here to scout this time.”
Park Joo-hyuk said.
“Scout?”
“Don’t you want to be a lawyer for Inhaus?”
“At Avio?”
“My boss says it’s more than one thing he wants you to do. Your salary will be guaranteed more than you earn now.”
“······.”
“What’s that look? You don’t like it?”
“It’s good to pay a lot of money, but somehow, if I become an inhouse, the amount of work will be several times as much as it is now.”
“I heard about some items and business directions while I was eating. I expect it to be tens of times, not many times.
“Insane·····.”
“Don’t worry, you won’t do it alone. I’m going to set up an in-house legal team and I’m going to have a few patent experts in it. And if you join the company, your work-life balance will be better than it is now.”
“It’s getting better.
“Our company keeps the 52-hour workweek limit. Everybody get off work on time.”
“Really?”
Lee Hye-won was shocked.
“But you’re a startup. Is that possible?”
“It’s a company where all the basic research is completed in the CEO’s head.”
“I’ll be right there. Where’s the contract? I’d like to sign it now.”
Lee Hye-won said quickly in case she missed the chance.
“Okay, I’ll probably start with moving probiotics when I get in. The CEO asked you to do that before, right?”
“Yes, I’m talking to the patent law office at Eisen’s 6th Laboratory.”
“Okay, take care of it after you join the company. You’ll have to do it alone for a while. I can discuss it with the CEO, but I’ll probably have to skype it.”
“Skype? Why?”
“I’m going on a business trip to America soon.”
“In America?”
Is there anything to be invested in in the United States. Lee Hye-won tilted her head.
Park Joo-hyuk said.
“I’m going to the International Society for Integrated Cerebral Diseases. They’re going to announce the results of Alzheimer’s clinical trials with stem cells and bring in funding.”
I’m The Only One With Genius DNA chapter 51
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