I’m The Only One With Genius DNA 121

I’m The Only One With Genius DNA chapter 121

Royal Swedish Academy of Sciences (8)

Science editor Samuel was thrilled to read the morning newsletter.

“Jessie! Jessie! Have a business trip!”

He shouted urgently.

“Korea?”

Jessie, who almost became Ryu Young-joon’s exclusive interviewer, asked.

“No, Sweden.”

“Oh! What’s going on? “Carolinskana Lund University? Dr. Ryu Young-joon has dominated the scientific community these days, so it’s time for a counterattack paper from the West.”

Jessie asked, glad to hear that.

“It’s Dr. Ryu’s.”

“What?”

Jesse’s eyes narrowed.

“Dr. Ryu took the researchers to a conference in Sweden, where he researched in two weeks and made a paper.”

“…. Does that make sense?”

“What did he do that made sense? Anyway, go ahead. This is important.”

“Was there anything that Dr. Ryu didn’t do that was not important?”

Jessie imitated Samuel’s tone of voice.

“You must have made another great new drug.”

She approached Samuel and asked.

“We’ve reported the adverse effects of immunograft inhibitors.”

Immunity gate inhibitor?

“It’s Dr. Oliver’s technology developed at Cold Spring Ever Laboratory.

“The most famous technology in the next generation of immunotherapy drugs. If you administer it to a lung cancer patient with an EGFR mutation, hyperprogramming the tumor can occur.”

“Hyperprogress?”

Jessie was appalled.

“This isn’t just a side effect, is it?”

“I know, it’s not a side effect, it’s a completely adverse effect. And this, I think, should be followed by an additional explanation for the paper. This is the paper that Nature gave the most strength two years ago. And that’s what Cold Spring Ever Laboratory and Jamie Anderson are doing the most recently.”

“…….”

“Maybe some pretty sharp words can come and go in the scientific community. The Jamie Anderson faction and the opposition could be fighting over Dr. Ryu Young-joon.”

“I’ll be back.”

Jessie said.

***

Hyperprogramming occurred in all mice administered more than 100 micrograms of immunogate inhibitors. The mice, which were administered in small doses, were not fatal, but were worse off.

Rats with more than a milligram of medication did not survive after eight days.

As everyone became worse than mice that had no medication taken care of, it seemed clear that the new drug had “killed” the mice.

The data are an important security target because it is an unpublished paper.

However, Ryu revealed it to Harriet and other judges and Oliver and Kagekuni.

They gathered them in a small seminar room and released the data.

“As you can see, all but four of the 20 mice with less than 1 microgram of drugs were hyperprogrammed, and most of them died.”

Ryu Young-joon announced.

He put data on mice’s tumor size and weight changes on the presentation screen.

It was clear that the change in tumor size was linked to the dose of immunogate inhibitors.

The more inhibitors are administered, the faster hyperprogressions occur in mice, the faster the tumor grows, and the faster the mice die.

“The lung cancer cells were originally derived from the body of a lung cancer patient who was hospitalized in Karolinska 20 years ago.”

Ryu Young-joon said.

“What would happen if the patient had been given immunogate inhibitors? At least this drug is dangerous in NSCLC-type lung cancer with EGFR mutations.”

There was silence among the scientists.

Professor Harriet felt very embarrassed.

Indeed, as Ryu said, hyperprogress has occurred.

Indeed, as Ryu said, hyperprogress has occurred.

At this point, it is not science but prophecy.

“How does that hyperprogram happen? Could you tell me about the mechanism?”

One of the doctors asked.

“Yes, of course. We also checked the mechanism. Let’s look at the next data.”

Ryu Young-joon flipped the slide.

“As you can see, it has been confirmed that the expression of EGFR has been amplified. In cancer cells of this type, the EGFR signal is strengthened and the cancer explodes.”

“Dr. Ryu.”

Jamie Anderson said.

“One of the patients at Karolinska Hospital was given immunogate inhibitors.”

Ryu Young-joon’s eyes got bigger.

“What? What kind of lung cancer is it?”

“As Dr. Ryu wrote, it’s NSCLC.”

“This is Professor Marcus’s patient here. Professor Marcus, please explain yourself.”

A lung cancer specialist, who looks about in his early 60s, spoke heavily.

“The patient is 62 years old and has stage 3 lung cancer. Other treatments no longer listened to, and the only hope was a productive immunogate inhibitor. I was originally going to use the medicine, but Professor Oliver, who developed the cure, was here, so I asked for advice.”

Professor Marcus said.

“Of course, we don’t know if there’s an EGFR mutation in the lung cancer. We need to check it out with the DNA analyzer. As CEO Ryu said, we don’t know if hyperprogress occurs when there is an EGFR mutation.”

“…….”

“But fortunately, so far there are no signs of that. What’s certain now is that the cancer is being removed from the patient’s body. It’s down by half now.”

“…….”

Ryu Young-joon’s face turned white.

“Well, well.”

Professor Markus said, Jamie Anderson stepped in, clearing his throat.

“Dr. Ryu, immunoguard inhibitors are good drugs. It can effectively capture a wide variety of cancers, including lung cancer… ”

“Stop taking medication right now!”

Ryu Young-joon shouted.

“What the hell have you done? Didn’t you know I was testing the drug? Even if there’s no other way, do you administer the hyperprogressive drug to the patient? You could’ve waited for the test results to come out! Or check the EGFR!”

“The tumor has been reduced to less than half!”

Jamie shouted face to face.

“Dr. Ryu, I don’t know how you got that data from a rat trial, but immunoguardant is a new drug approved by the FDA through all of its rigorous clinical trials! There are no side effects, and it is definitely curbing tumor growth!”

“NSCLC has mostly EGFR mutations!”

Ryu Young-joon banged the desk! He said with a bang.

“Professor, hyperprogress doesn’t come right away. In the beginning, there is definitely an effect of reducing tumors by immunogwan inhibitors.”

Ryu Young-joon opened other materials with a computer.

This is data for the first three days.

The size of the tumor was becoming noticeably smaller.

However, it suddenly returned to normal on the fourth day and exploded on the fifth day.

“The initial inhibition is like an incubation period. Cancer cells in new drugs begin to express EGFR in large quantities. It just takes time to make it! From the moment everything is expressed, the situation is reversed. The tumor doubles every six hours!”

Markus and other scientists looked confused.

Ryu Young-joon, who became frustrated, jumped down from the podium.

“Where is the patient now? Let’s start with EGFR.”

“…….”

“Dr. Ryu, let’s go together. I’m going to show you the video diagnostics.”

Marcus said.

***

Medical staff and scientists followed Marcus to the CT studio.

“Look.”

Marcus opened the files stored on the computer.

It was a tomographic picture of a patient’s lung cancer.

The tumor was almost the size of a fist in the old picture, but in the next picture Marcus showed, the tumor was almost halved.

The tumor was almost the size of a fist in the old picture, but in the next picture Marcus showed, the tumor was almost halved.

“This is a picture I took yesterday morning.”

Marcus said.

“How are you, Dr. Liu?”

“…….”

We can’t tell at this rate.

If lucky, there is no mutation in EGFR, so it can be treated as it is.

But what if he was a patient with an EGFR mutation?

Maybe it’s already out of hand.

The sea before the storm is still.

Clank.

The door to the CT room opened and nurses and young doctors appeared.

An older patient followed suit on a stretcher.

“Uh, Professor Marcus.”

The doctor looked at Marcus and said, glad to see him.

“I just contacted you because your patient complained of abdominal pain and vomiting, but did you come here after receiving it?”

“…Stomachache and vomiting? I’ve never heard of it before.….”

Marcus was embarrassed.

The patient lying on the stretcher was an NSCLC-type lung cancer patient with immunogate inhibitors.

“I see. I decided to do a CT scan on my own and came here. What should I do?”

“Let’s take a CT.”

Marcus said.

The patient has already been given contrast medium. He climbed up to the CT equipment and lay down on the bed.

The machine started working, and soon a tomographic photo appeared on the monitor.

Tok

Marcus dropped his pen.

The faces of the medical staff and scientists were appalled.

The tumor, which was reduced by 50 percent, was larger than before treatment in just one day.

“This is……. How could this be….….”

Marcus stammered.

“It’s a hyperprogress.”

Ryu Young-joon sighed.

***

After arriving in Sweden, Jesse did not meet Ryu Young-joon.

“I’m sorry, but it’s not the time for an interview or anything. There are three co-authors named as the first author of this project, so please interview them.”

Ryu Young-joon declined the interview with a short answer.

He was drinking coffee at a small cafe in Solna City.

Rosaline was sitting on the opposite chair.

Do you want to save the patient?

“Yes.”

Ryu Young-joon replied in a small voice.

– The patient doesn’t have much time. Hyperprogress has already begun, and moderation is difficult. He’ll probably die in a few days.

“Is there a way?”

Of course, I think of countless ways.

Rosalyn said as if she didn’t mean anything.

“But most of them are realistically difficult for me to proceed, right?”

Most of them are illegal. For example, mass inhalation of inhibitors of EGFR is administered to stop hyperprogressions.

“Do you have such inhibitors?”

I have to make it.

“It takes time to make it, doesn'”

So it’s a problem. You can rent or take one of these labs in Solna, synthesize it, skip all animal testing and clinical licensing processes, and put it in the patient’s nose to save it.

So it’s a problem. You can rent or take one of these labs in Solna, synthesize it, skip all animal testing and clinical licensing processes, and put it in the patient’s nose to save it.

“Experimental treatment is possible with the consent of Marcus and his patient, but it won’t agree to use any unknown chemicals that haven’t been tested.”

You’re already a miracle scientist who’s done a lot of things, so wouldn’t you just trust me and do it?

“Well, I might do it if you insist. But I don’t want to try with a vague possibility like ‘I might.'”

If you don’t do it, just force it secretly. Then I can save you.

“Then I’ll go to jail.”

Rosaline stamped her feet on the chair.

Then there’s no way.

“…….”

It’s possible to use Chimera immunotherapy, but it takes too much time.

Ryu Young-joon’s eyes, which were deep in thought, widened.

“Wait a minute. Chimera immunotherapy…….”

Why?

“Rosaline, I’m going to write a science fiction novel from now on, so please check the possibilities.”

Yes, go ahead.

“The Chimera immunotherapy is to take out the immune cells, manipulate the genes, and attach a new weapon.”

That’s right.

“And dendritic cells are cells that give immune cells information about cancer cells. Professor Kagekuni’s technique is to stimulate dendritic cells to help with the process.”

– That’s right.

“What if you fix it a little bit and let dendritic cells deliver genes to immune cells? What if we rearm the immune cells in the patient’s body immediately?”

asked Ryu Young-joon.

asked Ryu Young-joon.

“Wouldn’t we be able to skip the whole process of extracting immune cells from the patient’s body and manipulating genes and start doing chimera immunotherapy right away?”

I’m The Only One With Genius DNA chapter 121

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