I’m The Only One With Genius DNA 119

I’m The Only One With Genius DNA chapter 119

Royal Swedish Academy of Sciences (6)

Hyperprogress of cancer cells…….’

Ryu Young-joon read the message window.

Hyperprogression is a phenomenon in which cancer progresses explosively, causing tumors to multiply in an instantaneously.

“I’ll be out for a minute.”

Ryu Young-joon spoke to Professor Kagekuni and escaped into the hallway.

On the move he asked Rosaline.

Turn on the synchronization. How do you get the side effects?’

Oh, wait a minute. Let’s look at this in simulation mode, not synchronization mode.

The one I used to find anthrax?’

Yes.

‘That’s how it spreads in our country when there’s a virus, right?’

If you use a lot of fitness, you can do it. With less use, you can set up a virtual human being and test it with the medication you want. It looks perfect for the case like now.

All right, let’s do it.

[Simulation Mode]

Clack.

Ryu Young-joon pressed the button.

“LOL!”

A sharp pain broke out in my head.

My eyes turned black.

What? Rosaline?’

I don’t see anything. Jamie Anderson and Kagekuni all disappeared. I feel like I’m out of the classroom and suddenly fell into space.

The desk, computer, and chair all disappeared and the classroom floor turned black.

The foot wasn’t stepping on the floor.

‘What the hell is this…?’

Beep!

A message window popped up in front of my eyes again.

-Please enter the subject’s biological characteristics. [Extend.]

Biological properties?

Ryu Young-joon pressed the open button.

-Dyeing Body No. 1

-Dyeing Body No. 2

-Dyeing Body No. 3

…….

-Chromosome X

-Chromosome Y

Humans have 44 supernatant chromosomes and 2 sex chromosomes.

Half of them received from their fathers and half from their mothers, 22 of which are of the same type.

It is called in the same way as chromosome 1 and chromosome 2.

Ryu Young-joon pressed chromosome number 1.

– Protein expression gene

– Protein non-expression gene

– Similar genes

Inside the chromosome, there are countless genes, non-expression genes that control the expression of genes, or junk DNA that does nothing.

You mean you can choose all of them?

“Wait a minute……. This can’t be…….”

Ryu Young-joon’s body is slightly stiff.

Now I thought I’d been through a lot of surprises working with Rosaline, but I never imagined this.

Based on the 100 million genome project and DNA analysis technology, this is the future technology that we ultimately wanted to implement in reality.

Based on the 100 million genome project and DNA analysis technology, this is the future technology that we ultimately wanted to implement in reality.

Ryu Young-joon, although alone, has surpassed the course of those years through Rosaline.

We’ve reached the final stage of custom medicine.’

My heart is pounding.

Ryu Young-joon pressed the protein expression gene.

-AADACL3:Arylacetamide deacetylase-like 3.

-AADACL4:Arylacetamide deacetylase-like 4.

-ACAADM:acy-Coenzyme A dehydrogenase, C-4 to C-12 straight chain.

…….

It’s all genetic names.

As many as 2,064 genes appeared.

It’s all genes that exist in chromosome one.

“What the hell is all this…….”

I don’t know a single thing.

Honestly, how would anyone know this? Even a biologist can’t tell.

Even if you are an employee of the Korea Meteorological Administration, wouldn’t you know the humidity of the dundeok in the valley of a limestone cave in Singi-myeon, Gangwon-do? It’s the same as that.

Ryu Young-joon pressed the first gene that came to his mind.

ATGGCG…….

Now the DNA sequence of the AADACL3 gene has emerged. Each and every one of those sequences can be manipulated arbitrarily.

Ryu Young-joon’s shock has crossed the line.

Is this for real? Rosalyn, are you crazy?’

-Don’t be too touched. It’s not that difficult for me.

No matter how hard it is…….’

It is possible to edit ‘all letters of DNA’ equivalent to one billion characters.

Rosalyn can “set” the humidity of the limestone cave, which no one knows, beyond the “knowing” stage. The humidity of the first dune is 20 per cent. The temperature of the second puddle is 28 degrees. Like this.

It manipulates the weather of the entire planet in that much detail.

That’s an interesting analogy. So finish setting it up quickly and now observe where and when a typhoon breaks out in the Pacific Ocean.

‘…….’

This simulation can understand the human body mechanically. All the secrets of biology were open.

But when would I set up all 20,000 genes?’

Ryu Young-joon closed all of the detailed setup windows below by pressing the [fold] button next to the ‘-enter the subject’ message.

Please randomly set it to the patient type that can cause side effects when using immunogwan door inhibitors.’

I see.

Suddenly, a random imaginary patient popped up in front of Ryu Young-joon’s eyes.

He was quite an old, well-built man. The beard looked fluffy and Hispanic.

Beep!

His profile popped up in the message box on the right.

-63 years old, male.

-Height: 184.5 cm

-Weight: 105 kg

– Blood type : A

…….

Below came a wealth of data related to the lesion of the patient, and at the end, the extent of cancer development.

– Lung cancer: stage 3

-EGFR mutation driven.

‘EGFR?’

EGFR is an epithelial growth factor receptor.

When this receptor is stimulated, cells divide and multiply.

Some unlucky cells, however, may fail with EGFR.

The mutant EGFR sends splitting and proliferating signals inside the cell, even though there is no external stimulus.

The mutant EGFR sends splitting and proliferating signals inside the cell, even though there is no external stimulus.

The cell continues to divide and expand, leaving its designated position and swelling.

Then it becomes a tumor.

The word “EGFR mutation drive” means cancer caused by an EGFR mutation.

Ryu Young-joon immediately realized the problem.

Is immunogerms related to EGFR?’

He asked.

Yes, try administering immunoguardant to this hypothetical patient.

Beep!

A graphic of antibodies, which corresponds to immune gate inhibitors, came to mind.

Ryu Young-joon drags it by hand and drags it onto the virtual patient’s body.

[Setting How to Invest]

-Injection system

– Oral administration

-Patch

Immune duct inhibitors are injections.

Clack.

When the injection button was pressed, questions such as whether to inject the tumor, intravenously, how much to inject at a time, and how often to administer the injection.

“Oh, my God…….”

There are too many options.

“I don’t like to go to Subway because I don’t like having a lot of questions.”

Ryu chose intravenous injections and decided to administer 125 mg/m^2 per day for an hour.

m^2 is an expression of body surface area determined by height and weight.

The message finally came to mind.

Ryu Young-joon monitored the imaginary patient with a nervous mind.

The molecular phenomenon that takes place in the body unfolded in front of us.

Immune gate inhibitors, which entered the veins, spread rapidly throughout the body, and concentrated on the liver.

Dozens of genes were expressed in liver cells at once.

As the genes involved in the breakdown of proteins worked, element circuits began to spin quickly.

Proteinase stuck to immunogate inhibitors and was trying to break them down.

Some of the antibodies were broken, but a significant amount of them survived and continued to flow through the blood vessels.

And…….

“I’m going into lung cancer.

Ryu Young-joon’s mouth slowly opened.

Immune gate inhibitors permeated the tumor and began coordinating the fight between immune cells and cancer cells.

A new message window appeared.

Time values were rising from one to two days, three days, and one day per second. As proportionately, the level of lung cancer cell death was increasing rapidly.

And after a short time.

Beep!

[Hyperpropagation occurred.]

As the “immunocyte stop signal” of cancer cells was blocked, EGFR popped up as a complementary mechanism on the surface of cancer cells.

As the number of EGFRs increased, enormous pressure was being applied inside the tumor.

In just a few hours, cells began to double.

And

[Angiogenesis 발생]

New blood vessels crumbled into the tumor.

New blood vessels crumbled into the tumor.

[Time: 7 days]

The tumor has already grown more than five times larger than before the inhibitor was administered.

Lung cancer cells are beginning to spread.

[Time: 10 days]

[Cancer metastasized in breast tissue]

[Time: 14 days]

[The subject is dead]

[Simulation terminated]

-Exit

Ryu Young-joon pressed the exit button.

***

“For cancer patients with tumors due to mutations in EGFR, using immunogate inhibitors can be dangerous.”

Ryu Young-joon said.

It was a forum for mid-evaluation by the judges.

All the professors looked at Ryu Young-joon with embarrassed expressions.

“What does that mean?”

Jamie Anderson asked.

“Just as you heard. Side effects, or, to be precise, adverse effects. Inhibiting immune portal signals on the surface of cancer cells amplifies EGFR with its complementary effect. The use of inhibitors results in stronger adverse effects from EGFR amplification than the medicinal effects of immune cells from day 4. The proliferation of cancer cells goes beyond destructive efficiency. That’s when hyperprogramming starts. Cancer cells explode and can lead to death within a few days. Because EGFR mutations are quite common in cancer cells, this hyperprogress will occur in more than 10 percent of patients if the drug is used as it is.”

“…….”

Silence fell on the table.

“Dr. Ryu, are you serious? Do you have any evidence? Did you experiment?”

Jamie asked.

“There’s no experimental data, and it’s a theoretical guess.”

“If you don’t have experimental data, don’t talk like that. Immunogwan inhibitors have already been commercialized…….”

“Professor Harriet.”

Ryu Young-joon, chairman of the Nobel Committee at the Karolinska Institute of Medicine, said.

“I’d like to borrow your lab here.”

“The lab?”

“Yes.”

“You’re not going to experiment here?”

Professor Harriet asked in surprise.

“I’ll show you a rat experiment. Just sell me ten mice.”

“But they’re not EGFR mutants, they don’t have cancer.”

“We can make it.”

“…. Mr. Ryu. No matter how good Ryu is, can you experiment with animals of that size by yourself?”

“I can do it alone, but I’m not alone.”

“What?”

“We have the best dream team in science right now. The people I brought from Avio and Eisen I.”

“…….”

Professor Harriet said after a brief thought.

“I’ll give you a lab. And I’ll give you access to all the facilities in the Karolinska Medical School lab. How long do you need?”

“Two weeks. Thank you.”

Ryu Young-joon replied.

Ryu Young-joon, who came outside after the meeting, immediately took out his cell phone.

He sent full e-mails to top scientists now in Sweden via an in-house messenger.

I started a project at the Karolinska Institute of Medicine. I’m looking for a researcher who can help me with my experiment while staying for about two weeks. The first author of the Science paper, annual leave equivalent to the number of days used in the study, and monthly pay.]

Ring!

Park Dong-hyun, who received an e-mail notification, was shocked to see his cell phone.

“Wow, have you seen the chief? Is this for real?

Chun Ji-myung burst into laughter as he read the mail.

Chun Ji-myung burst into laughter as he read the mail.

“When you go back to Korea, I expected you to start a project to catch another cancer…”I didn’t expect you to start here.”

“Maybe you’re allergic to rest?”

“Our CEO?”

“How else in the world would anyone come all the way to Sweden to rent someone else’s lab and experiment?””

“I guess the idea of a subject that I can’t stand until I go back to Korea was attractive.”

“But isn’t that a boon? It’s a two-week study and a salary.”

“I know. The competition could be fierce. Where is the CEO now?”

asked Chun Ji-myung.

I’m The Only One With Genius DNA chapter 119

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